J. Fraser Glickman

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

Jessica Vincent, Carolina Adura, Pu Gao et al. · Nature Communications · 2017 · 360 citations · Full text

Primary Macrophages, Innate Immune System, Immunology +21

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lodoe Lama, Carolina Adura, Wei Xie et al. · Nature Communications · 2019 · 269 citations · Full text

MALT1 Small Molecule Inhibitors Specifically Suppress ABC-DLBCL In Vitro and In Vivo

Lorena Fontán, Chenghua Yang, Venkataraman Kabaleeswaran et al. · Cancer Cell · 2012 · 256 citations · Full text

Molecular Pharmacology, Novel Therapy, Medicine +9

Alzheimer's disease peptide β-amyloid interacts with fibrinogen and induces its oligomerization

Hyung Jin Ahn, Daria Zamolodchikov, Marta Cortés‐Canteli et al. · Proceedings of the National Academy of Sciences · 2010 · 214 citations

Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase.

James Inglese, J. Fraser Glickman, W Lorenz et al. · Journal of Biological Chemistry · 1992 · 197 citations · Full text