Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan et al. · Cell · 2000 · 3.4K citations

Natural Sciences, Genetics, Rna Biology +7

Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

Patrick Revy, Taro Muto, Yves Lévy et al. · Cell · 2000 · 1.6K citations · Full text

Mendelian Disorder, Autoimmune Disease, Genetic Disorder +8

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

Masamichi Muramatsu, V.S. Sankaranand, Shrikant Anant et al. · Journal of Biological Chemistry · 1999 · 1.1K citations · Full text

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Svend K. Petersen‐Mahrt, Reuben S. Harris, Michael S. Neuberger · Nature · 2002 · 884 citations

E. Coli, Antibody Diversification, Genetics +10

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Jayanta Chaudhuri, Ming Tian, Chan Khuong et al. · Nature · 2003 · 727 citations

Transcriptional Regulation, Natural Sciences, Oligonucleotide +5