Concepedia

Dna Lesion Processing

DNA Lesion Processing is a molecular mechanism within the broader category of DNA repair processes that specifically governs the recognition, excision, and resolution of chemically altered or mismatched nucleotides arising during somatic hypermutation to facilitate targeted antibody diversification.

121

Publications

8.6K

Citations

568

Authors

235

Institutions

Publications per year

2017–2026

24

Parents

Publications

121

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Jayanta Chaudhuri, Ming Tian, Chan Khuong et al. · Nature · 2003 · 734 citations

, , +9

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

Phuong Pham, Ronda Bransteitter, John Petruska et al. · Nature · 2003 · 660 citations

, , +8

Biochemistry of DNA Lesions

John F. Ward · Radiation Research · 1985 · 443 citations

, , +12

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

Jayanta Chaudhuri, Chan Khuong, Frederick W. Alt · Nature · 2004 · 376 citations

, , +5

UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'.

Roger Woodgate, Malini Rajagopalan, Charles Lu et al. · Proceedings of the National Academy of Sciences · 1989 · 226 citations · Full text

, , +13

1–5 of 121

Authors

568

  1. NA
    Nikita A. Kuznetsov

    Institute of Chemical Biology and Fundamental Medicine, Russia

    6 publications · 127 citations

    6

    h-index

  2. OS
    Olga S. Fedorova

    Institute of Chemical Biology and Fundamental Medicine, Russia

    6 publications · 127 citations

    6

    h-index

  3. MS
    Murat Saparbaev

    Centre National de la Recherche Scientifique, France

    3 publications · 136 citations

    3

    h-index

  4. SS
    Susan S. Wallace

    University of Vermont, United States

    3 publications · 164 citations

    3

    h-index

  5. OA
    Olga A. Kladova

    Institute of Chemical Biology and Fundamental Medicine, Russia

    3 publications · 84 citations

    3

    h-index

1–5 of 568

Institutions

235

  1. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    38 publications

    1.5K citations

  2. Novosibirsk State University

    Novosibirsk, Russia

    7 h-index

    23 publications

    572 citations

  3. Institute of Chemical Biology and Fundamental Medicine

    Novosibirsk, Russia

    7 h-index

    27 publications

    647 citations

  4. National Institutes of Health

    Bethesda, United States

    6 h-index

    20 publications

    1.8K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    14 publications

    6.2K citations

  6. Vanderbilt University

    Nashville, United States

    4 h-index

    19 publications

    580 citations

  7. Harvard University

    Cambridge, United States

    4 h-index

    14 publications

    4.9K citations

  8. University of Vermont

    Burlington, United States

    3 h-index

    8 publications

    481 citations

1–8 of 235

Venues

  1. Nucleic Acids Research

    19 publications · 892 citations

    16

    h-index

  2. Journal of Biological Chemistry

    JBC · 12 publications · 841 citations

    12

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 924 citations

    12

    h-index

  4. Biochemistry

    6 publications · 279 citations

    6

    h-index

  5. Molecular and Cellular Biology

    MCB · 5 publications · 566 citations

    5

    h-index

1–5