Concepedia

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Jayanta Chaudhuri, Ming Tian, Chan Khuong, Katrin F. Chua, Eric Pinaud, Frederick W. Alt

Nature · 2003 · 734 citations · 23 references

DOI

Concepts

References

23

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan et al. · Cell · 2000 · 3.4K citations

, , +14

Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

Patrick Revy, Taro Muto, Yves Lévy et al. · Cell · 2000 · 1.6K citations · Full text

, , +13

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

Masamichi Muramatsu, V.S. Sankaranand, Shrikant Anant et al. · Journal of Biological Chemistry · 1999 · 1.2K citations · Full text

, , +15

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Svend K. Petersen‐Mahrt, Reuben S. Harris, Michael S. Neuberger · Nature · 2002 · 888 citations

, , +12

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

Kefei Yu, Frédéric Chédin, Chih-Lin Hsieh et al. · Nature Immunology · 2003 · 746 citations

, , +13