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Significant compensatory role of position Y-2 conferring high affinity to non-phosphorylated inhibitors of Grb2-SH2 domain

Ya‐Qiu Long, Johannes Voigt, Feng-Di T. Lung, C. Richter King, Peter P. Roller

Bioorganic & Medicinal Chemistry Letters · 1999 · 25 citations · 11 references

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11

Controlling Epidermal Growth Factor (EGF)-stimulated Ras Activation in Intact Cells by a Cell-permeable Peptide Mimicking Phosphorylated EGF Receptor

Mauricio Rojas, Song‐Yi Yao, Yao-Zhong Lin · Journal of Biological Chemistry · 1996 · 235 citations · Full text

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Nonphosphorylated Peptide Ligands for the Grb2 Src Homology 2 Domain

Lyn Oligino, Feng‐Di T. Lung, Lakshmi Sastry et al. · Journal of Biological Chemistry · 1997 · 102 citations · Full text

, , +18

Structural and Conformational Requirements for High-Affinity Binding to the SH2 Domain of Grb2

Peter Ettmayer, Dennis S. France, John Gounarides et al. · Journal of Medicinal Chemistry · 1999 · 88 citations · Full text

, , +20

Potent Inhibition of Grb2 SH2 Domain Binding by Non-Phosphate-Containing Ligands

Zhu‐Jun Yao, C. Richter King, Tin Cao et al. · Journal of Medicinal Chemistry · 1998 · 77 citations · Full text

, , +18

Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands

Joseph Rahuel, Carlos Garcı́a-Echeverrı́a, Pascal Furet et al. · Journal of Molecular Biology · 1998 · 63 citations

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