Johannes Voigt

Comparison of the NCI Open Database with Seven Large Chemical Structural Databases

Johannes Voigt, Bruno Bienfait, Shaomeng Wang et al. · Journal of Chemical Information and Computer Sciences · 2001 · 217 citations

Bioorganic Chemistry, Databases, Molecular Biology +27

Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening

Claudio N. Cavasotto, Andrew Orry, Nicholas Murgolo et al. · Journal of Medicinal Chemistry · 2008 · 169 citations · Full text

Drug Target, G-protein-coupled Receptor, Molecular Biology +20

Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease

Jack D. Scott, Sarah W. Li, Andrew P. J. Brunskill et al. · Journal of Medicinal Chemistry · 2016 · 161 citations · Full text

Neurochemical Biomarkers, Peptide Science, Enzyme 1 +19

Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor

Jared N. Cumming, Elizabeth M. Smith, Lingyan Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 151 citations · Full text

Medicinal Chemistry, Drug Target, Active Bace1 Inhibitor +11

Discovery of Cyclic Acylguanidines as Highly Potent and Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I—Inhibitor Design and Validation

Zhaoning Zhu, Z. J. Sun, Yuanzan Ye et al. · Journal of Medicinal Chemistry · 2009 · 120 citations · Full text