Elizabeth M. Smith

Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist.

C. Chandra Kumar, M Malkowski, Z Yin et al. · PubMed · 2001 · 174 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor

Jared N. Cumming, Elizabeth M. Smith, Lingyan Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 154 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery of Cyclic Acylguanidines as Highly Potent and Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I—Inhibitor Design and Validation

Zhaoning Zhu, Z. J. Sun, Yuanzan Ye et al. · Journal of Medicinal Chemistry · 2009 · 121 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel μM Leads for the Development of nM BACE-1 (β-Site APP Cleaving Enzyme 1) Inhibitors

Yu‐Sen Wang, Corey Strickland, Johannes Voigt et al. · Journal of Medicinal Chemistry · 2009 · 101 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A coupled-enzyme equilibrium method for measuring urea in serum: optimization and evaluation of the AACC study group on urea candidate reference method.

Eric J. Sampson, M A Baird, C A Burtis et al. · Clinical Chemistry · 1980 · 100 citations

Life Sciences, Biochemistry, Electroanalytical Methods +12