Yu‐Sen Wang

Competition STD NMR for the detection of high‐affinity ligands and NMR‐based screening

Yu‐Sen Wang, Dingjiang Liu, Daniel F. Wyss · Magnetic Resonance in Chemistry · 2004 · 143 citations · Full text

Discovery of Cyclic Acylguanidines as Highly Potent and Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I—Inhibitor Design and Validation

Zhaoning Zhu, Z. J. Sun, Yuanzan Ye et al. · Journal of Medicinal Chemistry · 2009 · 120 citations · Full text

Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel μM Leads for the Development of nM BACE-1 (β-Site APP Cleaving Enzyme 1) Inhibitors

Yu‐Sen Wang, Corey Strickland, Johannes Voigt et al. · Journal of Medicinal Chemistry · 2009 · 101 citations · Full text

Non-Peptidic Small-Molecule Inhibitors of the Single-Chain Hepatitis C Virus NS3 Protease/NS4A Cofactor Complex Discovered by Structure-Based NMR Screening

Daniel F. Wyss, Ashok Arasappan, Mary M. Senior et al. · Journal of Medicinal Chemistry · 2004 · 51 citations · Full text

Structural Bioinformatics, Molecular Biology, Antiviral Drug +18

Interaction of a Novel GDP Exchange Inhibitor with the Ras Protein

A.K. Ganguly, Yu‐Sen Wang, Birendra N. Pramanik et al. · Biochemistry · 1998 · 48 citations

Nmr Spectroscopy, Cancer Biology, Tumor Biology +17