Concepedia

The Histidine Transporter SLC15A4 Coordinates mTOR-Dependent Inflammatory Responses and Pathogenic Antibody Production

Toshihiko Kobayashi, Shiho Shimabukuro-Demoto, Reiko Yoshida-Sugitani, Kaori Furuyama-Tanaka, Hitomi Karyu, Yuki Sugiura, Yukiko Shimizu, Toshiaki Hosaka, Motohito Goto, Norihiro Kato,

Immunity · 2014 · 164 citations · 34 references

DOIFull text

Open access

Concepts

References

34

IRF-7 is the master regulator of type-I interferon-dependent immune responses

Kenya Honda, Hideyuki Yanai, Hideo Negishi et al. · Nature · 2005 · 2.2K citations

, , +13

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H <sup>+</sup> -ATPase

Roberto Zoncu, Liron Bar‐Peled, Alejo Efeyan et al. · Science · 2011 · 1.6K citations · Full text

, , +17

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

Jonathan C. Kagan, Tian Su, Tiffany Horng et al. · Nature Immunology · 2008 · 1.2K citations

, , +12

Toll-like Receptor 7 and TLR9 Dictate Autoantibody Specificity and Have Opposing Inflammatory and Regulatory Roles in a Murine Model of Lupus

Sean R. Christensen, Jonathan Shupe, Kevin M. Nickerson et al. · Immunity · 2006 · 1.1K citations · Full text

, , +17

Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Taro Kawai, Shintaro Sato, Ken J. Ishii et al. · Nature Immunology · 2004 · 1K citations

, , +16