Polymorphism and Ultrastructural Organization of Prion Protein Amyloid Fibrils: An Insight from High Resolution Atomic Force Microscopy

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

Life Sciences, Biochemistry, Molecular Biology +17

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

Aneta T. Petkova, Richard D. Leapman, Zhihong Guo et al. · Science · 2005 · 1.7K citations

Life Sciences, Biochemistry, Neuroscience +17

NMR structure of the mouse prion protein domain PrP(121–231)

Roland Riek, Simone Hornemann, Gerhard Wider et al. · Nature · 1996 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +11

Scrapie prions aggregate to form amyloid-like birefringent rods

Stanley B. Prusiner, Michael P. McKinley, Karen A. Bowman et al. · Cell · 1983 · 1K citations

Life Sciences, Infectious Diseases, Molecular Biology +14

Synthetic Mammalian Prions

Giuseppe Legname, Ilia V. Baskakov, Hoang-Oanh B. Nguyen et al. · Science · 2004 · 1K citations

Life Sciences, Neurology, Neuroscience +17