Concepedia

Amyloid Fibril Structure

Amyloid Fibril Structure is a structural biology construct that refers to the highly ordered, β-sheet-rich, filamentous protein aggregate morphology characterized by its insolubility, resistance to proteolysis, and specific cross-β architecture, distinguishing it from other protein folding states such as native globular or amorphous aggregates.

2.7K

Publications

220.7K

Citations

9.4K

Authors

2.1K

Institutions

Publications per year

2017–2026

824

Parents

Publications

2.7K

Consort 2010 statement: extension to cluster randomised trials

Marion Campbell, Gilda Piaggio, Diana R Elbourne et al. · BMJ · 2012 · 3.6K citations · Full text

, , +17

Atomic structures of amyloid cross-β spines reveal varied steric zippers

M.R. Sawaya, Shilpa Sambashivan, Rebecca A. Nelson et al. · Nature · 2007 · 2.3K citations

, , +16

Structure of the cross-β spine of amyloid-like fibrils

Rebecca A. Nelson, M.R. Sawaya, Melinda Balbirnie et al. · Nature · 2005 · 2.2K citations · Full text

, , +14

A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR

Aneta T. Petkova, Yoshitaka Ishii, John J. Balbach et al. · Proceedings of the National Academy of Sciences · 2002 · 1.8K citations

, , +17

Common core structure of amyloid fibrils by synchrotron X-ray diffraction 1 1Edited by F. E. Cohen

Margaret Sunde, Louise C. Serpell, Mark Bartlam et al. · Journal of Molecular Biology · 1997 · 1.7K citations

, , +17

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Authors

9.4K

  1. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    68 publications · 11.7K citations

    53

    h-index

  2. RM
    Raffaele Mezzenga

    ETH Zurich, Switzerland

    46 publications · 5.9K citations

    36

    h-index

  3. RT
    Robert Tycko

    National Institute of Diabetes and Digestive and Kidney Diseases, United States

    39 publications · 13.2K citations

    35

    h-index

  4. PW
    Per Westermark

    Uppsala University, Sweden

    48 publications · 5.9K citations

    33

    h-index

  5. MF
    Marcus Fändrich

    Universität Ulm, Germany

    42 publications · 5.3K citations

    30

    h-index

1–5 of 9.4K

Institutions

2.1K

  1. University of Cambridge

    Cambridge, United Kingdom

    56 h-index

    359 publications

    50.7K citations

  2. National Institutes of Health

    Bethesda, United States

    51 h-index

    255 publications

    65K citations

  3. ETH Zurich

    Zurich, Switzerland

    47 h-index

    308 publications

    36.1K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    44 h-index

    329 publications

    21.4K citations

  5. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    39 h-index

    156 publications

    63.1K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    39 h-index

    204 publications

    61K citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    37 h-index

    202 publications

    33K citations

  8. The University of Osaka

    Osaka, Japan

    34 h-index

    211 publications

    14.3K citations

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Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 106 publications · 24.3K citations

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  2. Journal of Molecular Biology

    JMB · 120 publications · 13.3K citations

    65

    h-index

  3. Biochemistry

    132 publications · 14.2K citations

    60

    h-index

  4. Journal of the American Chemical Society

    JACS · 102 publications · 10.6K citations

    59

    h-index

  5. Journal of Biological Chemistry

    JBC · 123 publications · 10.6K citations

    59

    h-index

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