Concepedia

Mutations in the APC tumour suppressor gene cause chromosomal instability

Riccardo Fodde, Jeroen Kuipers, Carla Rosenberg, Ron Smits, Menno F. Kielman, Cláudia Gaspar, Johan H. van Es, Cor Breukel, J. Wiegant, Rachel H. Giles,

Nature Cell Biology · 2001 · 719 citations · 36 references

DOI

Concepts

References

36

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

, , +17

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC <sup>−/−</sup> Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin et al. · Science · 1997 · 3.3K citations

, , +17

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

, , +17

Genetic instability in colorectal cancers

Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein · Nature · 1997 · 2K citations

, , +14

Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene

Li-Kuo Su, Kenneth W. Kinzler, Bert Vogelstein et al. · Science · 1992 · 1.5K citations

, , +16