Concepedia

Publication | Open Access

Dantrolene, a Therapeutic Agent for Malignant Hyperthermia, Inhibits Catecholaminergic Polymorphic Ventricular Tachycardia in a RyR2R2474S/+ Knock-In Mouse Model

DOIFull Paper Access

122

Citations

17

References

2010

Year

Shigeki Kobayashi, Masafumi Yano, Hitoshi Uchinoumi, Takeshi Suetomi, Takehisa Susa, Makoto Ono, Xiaojuan Xu, Hiroki Tateishi, Tetsuro Oda, Shinichi Okuda,
Circulation Journal

Abstract

Dantrolene prevents CPVT, presumably by inhibiting Ca(2+) leak through the RyR2.

References

YearCitations

Page 1