Concepedia

Dantrolene Therapy

Dantrolene Therapy is a pharmacological intervention classified under skeletal muscle relaxants, distinguished by its mechanism of action involving direct inhibition of calcium release from the sarcoplasmic reticulum in response to ryanodine receptor activation, thereby reducing spasticity without suppressing spinal reflexes.

411

Publications

16.6K

Citations

1.5K

Authors

535

Institutions

Publications per year

2017–2026

45

Variants

Dantrolene Treatment

Parents

Publications

411

Clinical Presentation, Treatment, and Complications of Malignant Hyperthermia in North America from 1987 to 2006

Marilyn Green Larach, Gerald A. Gronert, Gregory C. Allen et al. · Anesthesia & Analgesia · 2010 · 410 citations

, , +13

Dantrolene Inhibition of Ryanodine Receptor Ca2+Release Channels

Fangyi Zhao, Pin Li, S. R. Wayne Chen et al. · Journal of Biological Chemistry · 2001 · 323 citations · Full text

, , +17

Dantrolene in Human Malignant Hyperthermia A Multicenter Study

Mary Elizabeth Kolb, M. L. Horne, Robert Martz · Anesthesiology · 1982 · 295 citations · Full text

, , +11

Studies on the mechanism of action of dantrolene sodium

K.O. Ellis, John F. Carpenter · Naunyn-Schmiedeberg s Archives of Pharmacology · 1972 · 277 citations

, , +3

In vitroantioxidant properties of dantrolene sodium

Mehmet Emin Büyükokuroğlu, İlhami Gülçın, Münir Oktay et al. · Pharmacological Research · 2001 · 272 citations

, , +3

1–5 of 411

Authors

1.5K

  1. PD
    Paul D. Allen

    Brigham and Women's Hospital, United States

    8 publications · 430 citations

    8

    h-index

  2. GA
    Gerald A. Gronert

    Mayo Clinic, United States

    8 publications · 689 citations

    8

    h-index

  3. JR
    José R. López

    Brigham and Women's Hospital, United States

    8 publications · 357 citations

    8

    h-index

  4. ME
    Mehmet Emin Büyükokuroğlu

    Atatürk University, Türkiye

    8 publications · 527 citations

    8

    h-index

  5. JP
    Jerome Parness

    Johnson University, United States

    7 publications · 458 citations

    7

    h-index

1–5 of 1.5K

Institutions

535

  1. Norwich University

    Northfield, United States

    11 h-index

    36 publications

    1.9K citations

  2. University of Pennsylvania

    Philadelphia, United States

    8 h-index

    38 publications

    1.6K citations

  3. Atatürk University

    Erzurum, Türkiye

    8 h-index

    23 publications

    1.5K citations

  4. University of Minnesota

    Minneapolis, United States

    8 h-index

    27 publications

    2.8K citations

  5. Harvard University

    Cambridge, United States

    7 h-index

    10 publications

    773 citations

  6. Instituto Venezolano de Investigaciones Científicas

    San Antonio de Los Altos, Venezuela

    7 h-index

    10 publications

    417 citations

  7. Yamaguchi University

    Yamaguchi, Japan

    7 h-index

    57 publications

    4.2K citations

  8. Boston Biomedical Research Institute

    Watertown, United States

    7 h-index

    14 publications

    1.5K citations

1–8 of 535

Venues

  1. Anesthesiology

    33 publications · 1.6K citations

    23

    h-index

  2. PubMed

    Repository · 38 publications · 1.1K citations

    21

    h-index

  3. Anesthesia & Analgesia

    19 publications · 1.1K citations

    17

    h-index

  4. European Journal of Pharmacology

    EJP · 14 publications · 301 citations

    13

    h-index

  5. Anaesthesia

    9 publications · 270 citations

    9

    h-index

1–5