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Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

BiochemistryMitochondrial FunctionMedicineLiver PhysiologyLipid PeroxidationCell DeathHuman HepatocytesAerobically-poised Hepg2 CellsHepatotoxicityMetabolomicsMetabolismPharmacologyCell BiologyLactate ProductionOxidative Stress