Yvonne Will

Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants

Lisa D. Marroquin, James T. Hynes, James A. Dykens et al. · Toxicological Sciences · 2007 · 639 citations

Life Sciences, Biochemistry, Cell Biology +17

Mitochondrial localization of estrogen receptor β

Shao-Hua Yang, Ran Liu, Evelyn J. Perez et al. · Proceedings of the National Academy of Sciences · 2004 · 501 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +12

Defining Desirable Central Nervous System Drug Space through the Alignment of Molecular Properties, in Vitro ADME, and Safety Attributes

Travis T. Wager, Ramalakshmi Y. Chandrasekaran, Xinjun Hou et al. · ACS Chemical Neuroscience · 2010 · 483 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

James A. Dykens, Joseph Jamieson, Lisa D. Marroquin et al. · Toxicology and Applied Pharmacology · 2008 · 222 citations

Life Sciences, Biochemistry, Pharmacology +17

Effect of the Multitargeted Tyrosine Kinase Inhibitors Imatinib, Dasatinib, Sunitinib, and Sorafenib on Mitochondrial Function in Isolated Rat Heart Mitochondria and H9c2 Cells

Yvonne Will, James A. Dykens, Sashi Nadanaciva et al. · Toxicological Sciences · 2008 · 215 citations

Life Sciences, Oncology, Pharmacology +17