James A. Dykens

Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants

Lisa D. Marroquin, James T. Hynes, James A. Dykens et al. · Toxicological Sciences · 2007 · 630 citations

Mitochondrial localization of estrogen receptor β

Shao-Hua Yang, Ran Liu, Evelyn J. Perez et al. · Proceedings of the National Academy of Sciences · 2004 · 496 citations · Full text

Isolated Cerebral and Cerebellar Mitochondria Produce Free Radicals when Exposed to Elevated Ca²⁺ and Na⁺: Implications for Neurodegeneration

James A. Dykens · Journal of Neurochemistry · 1994 · 495 citations

Mechanism of Kainate Toxicity to Cerebellar Neurons In Vitro Is Analogous to Reperfusion Tissue Injury

James A. Dykens, Arnold Stern, Ekkhart Trenkner · Journal of Neurochemistry · 1987 · 332 citations

Lipid Peroxidation, Cell Death, Reperfusion Tissue Injury +23

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

James A. Dykens, Joseph Jamieson, Lisa D. Marroquin et al. · Toxicology and Applied Pharmacology · 2008 · 220 citations

Biochemistry, Mitochondrial Function, Medicine +12