Sashi Nadanaciva

Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial

Yi‐Long Wu, Ying Cheng, Xiangdong Zhou et al. · The Lancet Oncology · 2017 · 1.2K citations

Oncology, Pathology, Bronchial Neoplasm +9

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

James A. Dykens, Joseph Jamieson, Lisa D. Marroquin et al. · Toxicology and Applied Pharmacology · 2008 · 220 citations

Biochemistry, Mitochondrial Function, Medicine +12

Effect of the Multitargeted Tyrosine Kinase Inhibitors Imatinib, Dasatinib, Sunitinib, and Sorafenib on Mitochondrial Function in Isolated Rat Heart Mitochondria and H9c2 Cells

Yvonne Will, James A. Dykens, Sashi Nadanaciva et al. · Toxicological Sciences · 2008 · 213 citations

Cardiovascular Toxicity, Mitophagy, Mitochondrial Disease +12

A high content screening assay for identifying lysosomotropic compounds

Sashi Nadanaciva, Shuyan Lu, David F. Gebhard et al. · Toxicology in Vitro · 2010 · 202 citations

Biochemistry, Medicine, Natural Sciences +8

In Vitro Assessment of Mitochondrial Dysfunction and Cytotoxicity of Nefazodone, Trazodone, and Buspirone

James A. Dykens, Joseph Jamieson, Lisa D. Marroquin et al. · Toxicological Sciences · 2008 · 193 citations · Full text

Mitochondrial Toxicity, Pharmacological Study, Mitochondrial Function +15