Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +11

<i>miR-15</i> and <i>miR-16</i> induce apoptosis by targeting BCL2

Amelia Cimmino, George A. Calin, Muller Fabbri et al. · Proceedings of the National Academy of Sciences · 2005 · 3.5K citations · Full text

Hematological Malignancy, Cancer Research, Chronic Lymphocytic Leukemia +15

BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

Emily H. Cheng, Michael C. Wei, Solly Weiler et al. · Molecular Cell · 2001 · 1.7K citations · Full text

Mitochondrial Function, Apoptosis, Immunology +6

bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia

M Hanada, D Delia, Antonella Aiello et al. · Blood · 1993 · 652 citations

Induction of Apoptosis in Cancer Cells by Bilberry (<i>Vaccinium myrtillus</i>) and the Anthocyanins

Naomi Katsube, Keiko Iwashita, Tojiro Tsushida et al. · Journal of Agricultural and Food Chemistry · 2002 · 435 citations

Edible Berries, Biochemistry, Medicine +15