Concepedia

Pro-apoptotic Agents

Pro-Apoptotic Agents is a class of pharmacological compounds that induce programmed cell death by selectively activating intrinsic or extrinsic apoptotic pathways in target cells.

1.4K

Publications

64.1K

Citations

8.4K

Authors

1.9K

Institutions

Publications per year

2017–2026

392

Variants

Pro-apoptotic Compounds

Parents

Publications

1.4K

Anti-cancer activity of targeted pro-apoptotic peptides

H. Michael Ellerby, Wadih Arap, Lisa Ellerby et al. · Nature Medicine · 1999 · 930 citations

, , +14

Ethanolic Extract of Propolis (EEP) Enhances the Apoptosis- Inducing Potential of TRAIL in Cancer Cells

Ewelina Szliszka, Zenon Czuba, Maciej Domino et al. · Molecules · 2009 · 804 citations · Full text

, , +17

Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol

Franziska B. Mullauer, Jan H. Kessler, Jan Paul Medema · PLoS ONE · 2009 · 695 citations · Full text

, , +14

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32

Elizabeth A. Slee, Huijun Zhu, Sek C. Chow et al. · Biochemical Journal · 1996 · 495 citations · Full text

, , +15

Phase I Dose-Escalation Study of Recombinant Human Apo2L/TRAIL, a Dual Proapoptotic Receptor Agonist, in Patients With Advanced Cancer

Roy S. Herbst, S. Gail Eckhardt, Razelle Kurzrock et al. · Journal of Clinical Oncology · 2010 · 440 citations

, , +17

1–5 of 1.4K

Authors

8.4K

  1. DC
    D. Clive Williams

    Trinity College Dublin, Ireland

    8 publications · 255 citations

    8

    h-index

  2. DM
    Daniela M. Zisterer

    Trinity College Dublin, Ireland

    7 publications · 241 citations

    7

    h-index

  3. EN
    Ettore Novellino

    University of Naples Federico II, Italy

    7 publications · 239 citations

    7

    h-index

  4. QP
    Q. Ping Dou

    The Barbara Ann Karmanos Cancer Institute, United States

    7 publications · 510 citations

    7

    h-index

  5. RC
    René Csük

    Martin Luther University Halle-Wittenberg, Germany

    6 publications · 190 citations

    6

    h-index

1–5 of 8.4K

Institutions

1.9K

  1. Inserm

    Paris, France

    21 h-index

    108 publications

    4.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    110 publications

    4.8K citations

  3. University of Naples Federico II

    Naples, Italy

    15 h-index

    50 publications

    2.4K citations

  4. Jilin University

    Changchun, China

    14 h-index

    71 publications

    2.7K citations

  5. Harvard University

    Cambridge, United States

    14 h-index

    64 publications

    3.3K citations

  6. University of Salerno

    Fisciano, Italy

    14 h-index

    62 publications

    2.2K citations

  7. King Abdulaziz University

    Jeddah, Saudi Arabia

    14 h-index

    82 publications

    2.5K citations

  8. Chinese Academy of Sciences

    Beijing, China

    14 h-index

    64 publications

    2.3K citations

1–8 of 1.9K

Venues

  1. PLoS ONE

    44 publications · 2.7K citations

    30

    h-index

  2. PubMed

    Repository · 67 publications · 3.4K citations

    29

    h-index

  3. European Journal of Medicinal Chemistry

    37 publications · 1.6K citations

    27

    h-index

  4. Journal of Medicinal Chemistry

    20 publications · 1.4K citations

    20

    h-index

  5. International Journal of Molecular Sciences

    IJMS · 31 publications · 832 citations

    19

    h-index

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