Jan H. Kessler

Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol

Franziska B. Mullauer, Jan H. Kessler, Jan Paul Medema · PLoS ONE · 2009 · 695 citations · Full text

Medicine, Oncology, Pharmacology +14

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

Daniel K. Wells, Marit M. van Buuren, Kristen K. Dang et al. · Cell · 2020 · 536 citations · Full text

Life Sciences, Immunology, Oncology +16

Efficient Identification of Novel Hla-A*0201–Presented Cytotoxic T Lymphocyte Epitopes in the Widely Expressed Tumor Antigen Prame by Proteasome-Mediated Digestion Analysis

Jan H. Kessler, N. J. C. M. Beekman, Sandra A. Bres-Vloemans et al. · The Journal of Experimental Medicine · 2001 · 264 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Broad in vitro efficacy of plant-derived betulinic acid against cell lines derived from the most prevalent human cancer types

Jan H. Kessler, Franziska B. Mullauer, Guido M. de Roo et al. · Cancer Letters · 2006 · 187 citations

Medicine, Cancer Biology, Oncology +9

Betulinic acid delivered in liposomes reduces growth of human lung and colon cancers in mice without causing systemic toxicity

Franziska B. Mullauer, Louis van Bloois, Joost Daalhuisen et al. · Anti-Cancer Drugs · 2011 · 108 citations

Pharmacy, Oncology, Pharmacology +17