Concepedia

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

Daniel K. Wells, Marit M. van Buuren, Kristen K. Dang, Vanessa M. Hubbard-Lucey, Kathleen C. F. Sheehan, Katie M. Campbell, Andrew Lamb, Jeffrey P. Ward, John Sidney, Ana-Belén Blázquez,

Cell · 2020 · 536 citations · 59 references

DOIFull text

Open access

Concepts

References

59

Amino acid substitution matrices from protein blocks.

Steven Henikoff, Jorja G. Henikoff · Proceedings of the National Academy of Sciences · 1992 · 6.4K citations

, , +16

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

Robert Samstein, Chung‐Han Lee, Alexander N. Shoushtari et al. · Nature Genetics · 2019 · 4.4K citations · Full text

, , +14

An immunogenic personal neoantigen vaccine for patients with melanoma

Patrick A. Ott, Zhuting Hu, Derin B. Keskin et al. · Nature · 2017 · 2.9K citations

, , +12

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Uğur Şahin, Evelyna Derhovanessian, Matthias Miller et al. · Nature · 2017 · 2.5K citations

, , +14

The Immune Epitope Database (IEDB): 2018 update

Randi Vita, Swapnil Mahajan, James A. Overton et al. · Nucleic Acids Research · 2018 · 2.3K citations · Full text

, , +15