An immunogenic personal neoantigen vaccine for patients with melanoma

Patrick A. Ott, Zhuting Hu, Derin B. Keskin, +37

Nature

VaccinationTumor ImmunologyMelanomaImmunologyTherapeutic Vaccine +3

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

Derin B. Keskin, Annabelle Anandappa, Jing Sun, +48

Nature

Neuro-oncologyTumor ImmunologyCancer ImmunosurveillanceGliomaImmunology +8

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

Zhuting Hu, Donna Leet, Rosa Lundbye Allesøe, +38

Nature Medicine

VaccinationTumor ImmunologyEpitope SpreadingCancer ImmunosurveillancePersonal Neoantigen Vaccines +9

Mechanism of EBV inducing anti-tumour immunity and its therapeutic use

Il‐Kyu Choi, Zhe Wang, Qiang Ke, +12

Nature

ImmunologyTumor ImmunityAnti-tumour ImmunityAntiviral TherapyAntiviral Response +4

A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens

Zhuting Hu, Annabelle Anandappa, Jing Sun, +23

Blood

Functional Heterogeneity in the CD4+ T Cell Response to Murine γ-Herpesvirus 68

Zhuting Hu, Marcia A. Blackman, Kenneth M. Kaye, +1

The Journal of Immunology

Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy

Nicholas L. Truex, Rebecca L. Holden, Binyou Wang, +11

Scientific Reports

CD4+ T-cell dependence of primary CD8+ T-cell response against vaccinia virus depends upon route of infection and viral dose

Zhuting Hu, Michael J. Molloy, Edward J. Usherwood

Cellular and Molecular Immunology

VaccinationViral DoseImmunologyAntiviral ResponseVirology +8

Strain-Dependent Requirement for IFN-γ for Respiratory Control and Immunotherapy in Murine Gammaherpesvirus Infection

Ching‐Yi Tsai, Zhuting Hu, Weijun Zhang, +1

Viral Immunology

ImmunodeficienciesViral PathogenesisImmunologyImmunodominanceCd4 T Cell Responses +14

Regulatory CD8+ T Cells Associated with Erosion of Immune Surveillance in Persistent Virus Infection Suppress In Vitro and Have a Reversible Proliferative Defect

Zhuting Hu, Weijun Zhang, Edward J. Usherwood

The Journal of Immunology

Adaptive Immune SystemT Cell MemoryT-regulatory CellImmunologyImmune Regulation +19