Jan Paul Medema

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe et al. · Autophagy · 2016 · 5.9K citations · Full text

The consensus molecular subtypes of colorectal cancer

Justin Guinney, Rodrigo Dienstmann, Xin Wang et al. · Nature Medicine · 2015 · 5K citations · Full text

Medicine, Pathology, Colorectal Cancer +4

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Louis Vermeulen, Felipe de Sousa e Melo, Maartje van der Heijden et al. · Nature Cell Biology · 2010 · 1.8K citations

Oncology, Medicine, Stem Cells +10

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)

Jan Paul Medema · The EMBO Journal · 1997 · 1.2K citations · Full text

Signal Transduction, Pathogenesis, Immunology +6

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost, Richard H. van Jaarsveld, Bas Ponsioen et al. · Nature · 2015 · 1.1K citations

Adult Stem Cell, Colorectal Cancer, Sequential Cancer Mutations +5