Felipe de Sousa e Melo

The consensus molecular subtypes of colorectal cancer

Justin Guinney, Rodrigo Dienstmann, Xin Wang et al. · Nature Medicine · 2015 · 5K citations · Full text

Medicine, Pathology, Colorectal Cancer +4

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Louis Vermeulen, Felipe de Sousa e Melo, Maartje van der Heijden et al. · Nature Cell Biology · 2010 · 1.8K citations

Oncology, Medicine, Stem Cells +10

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

Tim J. Schuijt, Jacqueline M. Lankelma, Brendon P. Scicluna et al. · Gut · 2015 · 808 citations · Full text

A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer

Felipe de Sousa e Melo, Antonina V. Kurtova, Jonathan M. Harnoss et al. · Nature · 2017 · 771 citations

Metastatic Colon Cancer, Distinct Role, Medicine +11

Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions

Felipe de Sousa e Melo, Xin Wang, Marnix Jansen et al. · Nature Medicine · 2013 · 765 citations

Tumor Biology, Molecularly Distinct Subtype, Gastrointestinal Oncology +11