Concepedia

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

Diane Martindale, Abigail S. Hackam, Andrew Wieczorek, Lisa Ellerby, Cheryl L. Wellington, Krista McCutcheon, Roshni R. Singaraja, Parsa Kazemi‐Esfarjani, Richard M. Devon, Seung Up Kim,

Nature Genetics · 1998 · 484 citations · 24 references

DOI

Concepts

References

24

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

, , +14

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

, , +13

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed · 1987 · 3.8K citations

, , +11

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

, , +17

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

, , +16