Krista McCutcheon

A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration

John Hodgson, N. Agopyan, Claire‐Anne Gutekunst et al. · Neuron · 1999 · 828 citations · Full text

Neurodegenerative Diseases, Full-length Mutant Huntingtin, Selective Striatal Neurodegeneration +8

Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

Cheryl L. Wellington, Lisa Ellerby, Abigail S. Hackam et al. · Journal of Biological Chemistry · 1998 · 568 citations · Full text

Androgen Receptor, Genetics, Apoptosis +17

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

Diane Martindale, Abigail S. Hackam, Andrew Wieczorek et al. · Nature Genetics · 1998 · 483 citations

Intracellular Aggregates, Bioanalysis, Physiology +7

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

Michael A. Kalchman, Hiroshi Koide, Krista McCutcheon et al. · Nature Genetics · 1997 · 383 citations

Signal Transduction, Molecular Physiology, Molecular Neuroscience +12

The Influence of Huntingtin Protein Size on Nuclear Localization and Cellular Toxicity

Abigail S. Hackam, Roshni R. Singaraja, Cheryl L. Wellington et al. · The Journal of Cell Biology · 1998 · 313 citations · Full text

Neurodegenerative Diseases, Protein Function, Cell Division +15