Roshni R. Singaraja

A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration

John Hodgson, N. Agopyan, Claire‐Anne Gutekunst et al. · Neuron · 1999 · 828 citations · Full text

Neurodegenerative Diseases, Full-length Mutant Huntingtin, Selective Striatal Neurodegeneration +8

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

Collette K. Hand, Hitoshi Osuga, Yoshiko Yanagisawa et al. · Nature Genetics · 2001 · 675 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Genetics +7

Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

Cheryl L. Wellington, Lisa Ellerby, Abigail S. Hackam et al. · Journal of Biological Chemistry · 1998 · 568 citations · Full text

Androgen Receptor, Genetics, Apoptosis +17

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

Diane Martindale, Abigail S. Hackam, Andrew Wieczorek et al. · Nature Genetics · 1998 · 483 citations

Intracellular Aggregates, Bioanalysis, Physiology +7

Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy

Johane M. Robitaille, Marcia L.E. MacDonald, Ajamete Kaykas et al. · Nature Genetics · 2002 · 473 citations

Ocular Disease, Vitreous Body, Familial Exudative Vitreoretinopathy +6