Concepedia

TREX1 acts in degrading damaged DNA from drug-treated tumor cells

Chuan-Jen Wang, Wing Lam, Scott Bussom, Hua-Mei Chang, Yung‐Chi Cheng

DNA repair · 2009 · 37 citations · 40 references

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References

40

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

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Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

Yanick J. Crow, Bruce E. Hayward, Rekha Parmar et al. · Nature Genetics · 2006 · 892 citations

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Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus

Min Ae Lee‐Kirsch, Maolian Gong, Dipanjan Chowdhury et al. · Nature Genetics · 2007 · 725 citations

, , +10

Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease

Yun‐Gui Yang, Tomas Lindahl, Deborah E. Barnes · Cell · 2007 · 581 citations · Full text

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C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy

Anna Richards, Arn M. J. M. van den Maagdenberg, Joanna C. Jen et al. · Nature Genetics · 2007 · 452 citations

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