Concepedia

Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus

Min Ae Lee‐Kirsch, Maolian Gong, Dipanjan Chowdhury, Lydia Senenko, Kerstin Engel, Young‐Ae Lee, Udesh de Silva, Suzanna Bailey, Torsten Witte, Timothy J. Vyse,

Nature Genetics · 2007 · 725 citations · 12 references

DOI

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12

Recognition of Cytosolic DNA Activates an IRF3-Dependent Innate Immune Response

Daniel B. Stetson, Ruslan Medzhitov · Immunity · 2006 · 1K citations · Full text

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Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

Yanick J. Crow, Bruce E. Hayward, Rekha Parmar et al. · Nature Genetics · 2006 · 892 citations

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Features of systemic lupus erythematosus in Dnase1-deficient mice

Markus Napirei, Holger Karsunky, Branko Zevnik et al. · Nature Genetics · 2000 · 781 citations

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Mutation of DNASE1 in people with systemic lupus erythematosus

Koji Yasutomo, Takahiko Horiuchi, Shoji Kagami et al. · Nature Genetics · 2001 · 588 citations

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Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages

Kohki Kawane, Mayumi Ohtani, Keiko Miwa et al. · Nature · 2006 · 458 citations

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