Langerhans cells renew in the skin throughout life under steady-state conditions

Miriam Mérad, Markus G. Manz, Holger Karsunky, +6

Nature Immunology

Skin DevelopmentSteady-state ConditionsCutaneous BiologyImmunologyWound Healing +9

Features of systemic lupus erythematosus in Dnase1-deficient mice

Markus Napirei, Holger Karsunky, Branko Zevnik, +3

Nature Genetics

Autoimmune DiseaseSystemic Lupus ErythematosusSystemic Lupus Erythematosus TreatmentLupusMedicine +8

Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors

Antonio Cozzio, Emmanuelle Passegué, Paul M. Ayton, +3

Genes & Development

Mixed-phenotype Acute LeukemiaImmunologySimilar Mll-associated LeukemiasTumor BiologySelf-renewing Stem Cells +17

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

Hong Ji, Lauren I. R. Ehrlich, Jun Seita, +15

Nature

ChromatinComprehensive Methylome MapEpigenetic ChangeGeneticsEpigenomics +5

Flt3 Ligand Regulates Dendritic Cell Development from Flt3+ Lymphoid and Myeloid-committed Progenitors to Flt3+ Dendritic Cells In Vivo

Holger Karsunky, Miriam Mérad, Antonio Cozzio, +2

The Journal of Experimental Medicine

Flt3+ LymphoidLymphocyte DevelopmentT-regulatory CellImmunologySteady State Dcs +15

Repression of p15INK4b expression by Myc through association with Miz-1

Peter Staller, Karen Peukert, Astrid Kiermaier, +8

Nature Cell Biology

Transcriptional RegulationProtein ExpressionMolecular RegulationNatural SciencesMolecular Biology +6

Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1

Holger Karsunky, Hui Zeng, Thorsten Schmidt, +5

Nature Genetics

InflammationInflammatory ReactionsTranscriptional RegulationCytokineInflammatory Disease +12

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

Matthew A. Inlay, Deepta Bhattacharya, Debashis Sahoo, +6

Genes & Development

Lymphocyte DevelopmentEarliest StageCell ProliferationCommon Lymphoid ProgenitorsCell Specialization +19

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

Chi Wai Eric So, Holger Karsunky, Emmanuelle Passegué, +3

Cancer Cell

Hematological MalignancyMixed-phenotype Acute LeukemiaHematologyImmunologyAdult T-cell Leukemia-lymphoma +3

Identification of the earliest natural killer cell–committed progenitor in murine bone marrow

John W. Fathman, Deepta Bhattacharya, Matthew A. Inlay, +3

Blood