Features of systemic lupus erythematosus in Dnase1-deficient mice

Markus Napirei, Holger Karsunky, Branko Zevnik, +3

Nature Genetics

Autoimmune DiseaseSystemic Lupus ErythematosusSystemic Lupus Erythematosus TreatmentLupusMedicine +8

Host DNases prevent vascular occlusion by neutrophil extracellular traps

Miguel Jiménez-Alcázar, Chandini Rangaswamy, Rachita Panda, +15

Science

Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap–mediated sterile inflammation

Jan Rossaint, Jan M. Herter, Hugo Van Aken, +5

Blood

Murine serum nucleases – contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1‐like 3 (DNase1l3)

Markus Napirei, Sebastian Ludwig, Jamal Mezrhab, +2

FEBS Journal

ChromatinGenome InstabilityDnase1 Knockout MiceMurine Serum NucleasesBiochemistry +13

Impaired DNase1‐mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies

Miguel Jiménez-Alcázar, Markus Napirei, Rachita Panda, +7

Journal of Thrombosis and Haemostasis

InflammationThrombosisNeutrophil Extracellular TrapsGranulocyteHematology +10

Chromatin breakdown during necrosis by serum Dnase1 and the plasminogen system

Markus Napirei, Swantje Wulf, Hans Georg Mannherz

Arthritis & Rheumatism

Cisplatin Nephrotoxicity Is Mediated by Deoxyribonuclease I

Alexei G. Basnakian, Eugene O. Apostolov, Xiaoyan Yin, +3

Journal of the American Society of Nephrology

Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3)

Markus Napirei, Swantje Wulf, Dirk Eulitz, +2

Biochemical Journal

Dna AnalysisMolecular BiologyMolecular GeneticsMolecular ResearchProtein Expression +15

Expression pattern of the deoxyribonuclease 1 gene: lessons from the Dnase1 knockout mouse

Markus Napirei, Albert Ricken, Dirk Eulitz, +2

Biochemical Journal

Holocrine Secretion of Sebum Is a Unique DNase2-Dependent Mode of Programmed Cell Death

Heinz Fischer, Judith Fumicz, Heidemarie Rossiter, +4

Journal of Investigative Dermatology

ChromatinGenome InstabilityMolecular PhysiologyNatural SciencesApoptosis +10