Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

Features of systemic lupus erythematosus in Dnase1-deficient mice

Markus Napirei, Holger Karsunky, Branko Zevnik et al. · Nature Genetics · 2000 · 781 citations

Medicine, Immunology, Pathology +11

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

Yanick J. Crow, Andrea Leitch, Bruce E. Hayward et al. · Nature Genetics · 2006 · 673 citations

Life Sciences, Genetics, Molecular Biology +11

Mutation of DNASE1 in people with systemic lupus erythematosus

Koji Yasutomo, Takahiko Horiuchi, Shoji Kagami et al. · Nature Genetics · 2001 · 588 citations

Life Sciences, Genetics, Molecular Genetics +10

A Progressive familial encephalopathy in infancy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis

Jean Aicardi, Françoise Goutières · Annals of Neurology · 1984 · 482 citations

Medicine, Neurology, Neuroscience +17

Systemic Lupus Erythematosus: Presence in Human Serum of an Unusual Acid-Labile Leukocyte Interferon

Olivia T. Preble, Roberta Black, Robert M. Friedman et al. · Science · 1982 · 461 citations

Life Sciences, Immunology, Autoimmunity +13