Concepedia

Activation of p53 pathway by Nutlin-3a inhibits the expression of the therapeutic target α5 integrin in colon cancer cells

Hana Janoušková, Anne‐Marie Ray, Fanny Noulet, Isabelle Lelong-Rebel, Laurence Choulier, Florence Schaffner, Maxime Lehmann, Sophie Martin, Jan Teisinger, Monique Dontenwill

Cancer Letters · 2013 · 46 citations · 36 references

DOI

Concepts

References

36

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature · 2008 · 7.8K citations · Full text

, , +12

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Wen Xue, Lars Zender, Cornelius Miething et al. · Nature · 2007 · 2.4K citations

, , +16

Restoration of p53 function leads to tumour regression in vivo

Andrea Ventura, David G. Kirsch, Margaret E. McLaughlin et al. · Nature · 2007 · 1.8K citations

, , +12

Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors

Natalia Issaeva, Przemyslaw Bozko, Martin Enge et al. · Nature Medicine · 2004 · 744 citations

, , +15

A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis

Martina Kracikova, Gal Akiri, Ajish George et al. · Cell Death and Differentiation · 2013 · 268 citations · Full text

, , +16