Margaret E. McLaughlin

Prediction of central nervous system embryonal tumour outcome based on gene expression

Scott L. Pomeroy, Pablo Tamayo, Michelle Gaasenbeek et al. · Nature · 2002 · 2.4K citations

Neuro-oncology, Developmental Biology, Engineering +9

Restoration of p53 function leads to tumour regression in vivo

Andrea Ventura, David G. Kirsch, Margaret E. McLaughlin et al. · Nature · 2007 · 1.8K citations

P53 Function, Tumor Heterogeneity, Medicine +10

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

Hui Gao, Joshua M. Korn, Stéphane Ferretti et al. · Nature Medicine · 2015 · 1.4K citations

Tumor Biology, Radiology, Oncology +10

Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.

Catherine L. Nutt, D.R. Mani, Rebecca A. Betensky et al. · PubMed · 2003 · 959 citations

Histological Classification, Pathology, Class Prediction Methodology +19

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Jun Liu, Shifeng Pan, Mindy H. Hsieh et al. · Proceedings of the National Academy of Sciences · 2013 · 819 citations · Full text

Wnt Signaling, Tumor Biology, Signaling Pathway +19