Concepedia

Natalia Issaeva

NI

42

Publications

7.9K

Citations

28

H-Index

2002

Active since

Affiliations

Yale University(Current)

Karolinska Institutet

Yale Cancer Center

Stockholm University

University of North Carolina at Chapel Hill

Natalia Issaeva is an author at Yale University specializing in medicine, cell biology, and cancer research.

Top concepts

MedicineCell BiologyTumor BiologyCancer ResearchRadiation OncologyCancer BiologyCell DeathApoptosisCancer Cell BiologyOncology

Publications per year

2002–2023

42

Publications

42

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

Jiřina Bártková, Nousin Rezaei, Michalis Liontos et al. · Nature · 2006 · 1.9K citations

Oncogene-induced Senescence, Chromatin, Genome Instability +11

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

Vladimir J.N. Bykov, Natalia Issaeva, Alexandre Shilov et al. · Nature Medicine · 2002 · 1.1K citations

Tumor Biology, Medicine, Molecular Biology +9

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

Eva Petermann, Manuel Luís Orta, Natalia Issaeva et al. · Molecular Cell · 2010 · 824 citations · Full text

Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors

Natalia Issaeva, Przemyslaw Bozko, Martin Enge et al. · Nature Medicine · 2004 · 740 citations

P53 Function, Small Molecule Rita, Medicine +9

PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination

Helen E. Bryant, Eva Petermann, Niklas Schultz et al. · The EMBO Journal · 2009 · 589 citations · Full text

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