Concepedia

Vladimir J.N. Bykov

VJ

Statistics

Publications

45

Citations

5K

H-Index

32

Active since

1992

Affiliations

Karolinska Institutet(Current)

Karolinska University Hospital

Centre international de recherche sur le cancer

APR Technologies (Sweden)

S:t Eriks Ögonsjukhus

Vladimir J.N. Bykov is an author at Karolinska Institutet specializing in oncology, medicine, and molecular oncology.

ORCID

Publications per year

1992–2023

45

Publications

45

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

Vladimir J.N. Bykov, Natalia Issaeva, Alexandre Shilov et al. · Nature Medicine · 2002 · 1.1K citations

, , +13

PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

Jérémy Lambert, Petr Gorzov, Dmitry B. Veprintsev et al. · Cancer Cell · 2009 · 577 citations

, , +12

Targeting p53 in Vivo: A First-in-Human Study With p53-Targeting Compound APR-246 in Refractory Hematologic Malignancies and Prostate Cancer

Sören Lehmann, Vladimir J.N. Bykov, Dina Ali et al. · Journal of Clinical Oncology · 2012 · 404 citations · Full text

, , +17

PRIMA-1MET synergizes with cisplatin to induce tumor cell apoptosis

Vladimir J.N. Bykov, Nicole Zache, Hélène Stridh et al. · Oncogene · 2005 · 251 citations · Full text

, , +14

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Qiang Zhang, Vladimir J.N. Bykov, Klas G. Wiman et al. · Cell Death and Disease · 2018 · 251 citations · Full text

, , +14

1–5 of 45