Manuel Luís Orta

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

Eva Petermann, Manuel Luís Orta, Natalia Issaeva et al. · Molecular Cell · 2010 · 832 citations · Full text

Life Sciences, Biology, Molecular Biology +15

The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions

Manuel Luís Orta, Andreas Höglund, José Manuel Calderón‐Montaño et al. · Nucleic Acids Research · 2014 · 85 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I– and II–DNA Complexes in Cells

Estefanía Burgos‐Morón, José Manuel Calderón‐Montaño, Manuel Luís Orta et al. · Journal of Agricultural and Food Chemistry · 2012 · 77 citations

Medicine, Molecular Biology, Oncology +17

5-Aza-2′-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair

Manuel Luís Orta, José Manuel Calderón‐Montaño, Inmaculada Domı́nguez et al. · Nucleic Acids Research · 2013 · 75 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation

Petra Groth, Manuel Luís Orta, Ingegerd Elvers et al. · Nucleic Acids Research · 2012 · 74 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17