Concepedia

Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties

Dooseop Kim, Liping Wang, Jeffrey J. Hale, Christopher L. Lynch, Richard J. Budhu, Malcolm MacCoss, Sander G. Mills, Lorraine Malkowitz, Sandra L. Gould, Julie A. DeMartino,

Bioorganic & Medicinal Chemistry Letters · 2005 · 149 citations · 19 references

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19

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

Rong Liu, William A. Paxton, Sunny Choe et al. · Cell · 1996 · 3.1K citations · Full text

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Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Michel Samson, Frédérick Libert, Benjamin J. Doranz et al. · Nature · 1996 · 2.9K citations

, , +11

Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells

Daria J. Hazuda, Peter J. Felock, Marc Witmer et al. · Science · 2000 · 1.1K citations

, , +16

New nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties and structure-activity relationships of 2-alkylbenzimidazole derivatives

Andrew P. Thomas, C. Allott, Keith H. Gibson et al. · Journal of Medicinal Chemistry · 1992 · 91 citations · Full text

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3-Substituted 5,7-dimethylpyrazolo[1,5-a]pyrimidines, 3',5'-cyclic AMP phosphodiesterase inhibitors

Thomas Novinson, R. James Hanson, Mary K. Dimmitt et al. · Journal of Medicinal Chemistry · 1974 · 73 citations

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