Malcolm MacCoss

Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors

Mark S. Kramer, Neal R. Cutler, John P. Feighner et al. · Science · 1998 · 1.1K citations

Medicine, Pharmacology, Psychiatry +17

Inhibition of Hepatitis C Virus RNA Replication by 2′-Modified Nucleoside Analogs

Steven S. Carroll, Joanne E. Tomassini, Michele Bosserman et al. · Journal of Biological Chemistry · 2003 · 338 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Characterization of Resistance to Non-obligate Chain-terminating Ribonucleoside Analogs That Inhibit Hepatitis C Virus Replication in Vitro

Giovanni Migliaccio, Joanne E. Tomassini, Steven S. Carroll et al. · Journal of Biological Chemistry · 2003 · 325 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A 7-Deaza-Adenosine Analog Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic Properties

David B. Olsen, Anne B. Eldrup, Linda Bartholomew et al. · Antimicrobial Agents and Chemotherapy · 2004 · 234 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Structural Optimization Affording 2-(<i>R</i>)-(1-(<i>R</i>)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(<i>S</i>)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

Jeffrey J. Hale, Sander G. Mills, Malcolm MacCoss et al. · Journal of Medicinal Chemistry · 1998 · 205 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15