Jeffrey J. Hale

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

Suzanne Mandala, Richard Hajdu, James D. Bergstrom et al. · Science · 2002 · 1.7K citations

Lymphocyte Development, Immunology, Immunologic Mechanism +19

Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors

Mark S. Kramer, Neal R. Cutler, John P. Feighner et al. · Science · 1998 · 1.1K citations

Psychotropic Medication, Psychopharmacology, Antidepressant Activity +16

Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes

M J Forrest, S.-Y. Sun, Richard Hajdu et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 332 citations

Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice

Michael Webb, Chui‐Se Tham, Fen‐Fen Lin et al. · Journal of Neuroimmunology · 2004 · 222 citations

Molecular Immunology, Sjl Mice, Autoimmune Disease +13

Structural Optimization Affording 2-(<i>R</i>)-(1-(<i>R</i>)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(<i>S</i>)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

Jeffrey J. Hale, Sander G. Mills, Malcolm MacCoss et al. · Journal of Medicinal Chemistry · 1998 · 203 citations · Full text

Orally Active, Pharmacotherapy, Pharmaceutical Chemistry +21