Andrew P. Thomas

ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.

Stephen R. Wedge, Donald Ogilvie, Michael Dukes et al. · PubMed · 2002 · 802 citations

Medicine, Medicinal Chemistry, Pharmacology +15

AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

Paul R. Gavine, Lorraine Mooney, Elaine Kilgour et al. · Cancer Research · 2012 · 499 citations

Medicine, Oncology, Pharmacology +16

Integrating cytosolic calcium signals into mitochondrial metabolic responses

Lawrence D. Gaspers, P. J. Burnett, Guy A. Rutter et al. · The EMBO Journal · 1998 · 371 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Novel 4-Anilinoquinazolines with C-7 Basic Side Chains:  Design and Structure Activity Relationship of a Series of Potent, Orally Active, VEGF Receptor Tyrosine Kinase Inhibitors

Laurent Hennequin, Elaine S. E. Stokes, Andrew P. Thomas et al. · Journal of Medicinal Chemistry · 2002 · 308 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Mitochondria Suppress Local Feedback Activation of Inositol 1,4,5-Trisphosphate Receptors by Ca2+

György Hajnóczky, Richard Hager, Andrew P. Thomas · Journal of Biological Chemistry · 1999 · 265 citations · Full text

Life Sciences, Cell Biology, Physiology +17