Elaine S. E. Stokes

ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.

Stephen R. Wedge, Donald Ogilvie, Michael Dukes et al. · PubMed · 2002 · 802 citations

Oral Administration, Pharmacotherapy, Tumor Biology +18

Novel 4-Anilinoquinazolines with C-7 Basic Side Chains:  Design and Structure Activity Relationship of a Series of Potent, Orally Active, VEGF Receptor Tyrosine Kinase Inhibitors

Laurent Hennequin, Elaine S. E. Stokes, Andrew P. Thomas et al. · Journal of Medicinal Chemistry · 2002 · 308 citations · Full text

Combinatorial Chemistry, Tyrosine Kinase, Orally Active +16

Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors

Laurent Hennequin, Andrew P. Thomas, Craig Johnstone et al. · Journal of Medicinal Chemistry · 1999 · 235 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +15

ZD4190: an orally active inhibitor of vascular endothelial growth factor signaling with broad-spectrum antitumor efficacy.

Stephen R. Wedge, DJ Ogilvie, Michael Dukes et al. · PubMed · 2000 · 194 citations

Chemoprevention Strategy, Immunology, Pathology +18

An Industry Perspective on Forced Degradation Studies of Biopharmaceuticals: Survey Outcome and Recommendations

Jennifer Halley, Yite Robert Chou, Crystal Cicchino et al. · Journal of Pharmaceutical Sciences · 2019 · 68 citations

Quality Deterioration, Environmental Engineering, Forced Degradation Studies +8