Richard J. Budhu

Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties

Dooseop Kim, Liping Wang, Jeffrey J. Hale et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 148 citations · Full text

Fused Heterocycles, Antiviral Activity, Medicine +11

Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs

Jeffrey J. Hale, Sander G. Mills, Malcolm MacCoss et al. · Journal of Medicinal Chemistry · 2000 · 95 citations · Full text

Regioselective Dibenzylphosphorylation, Biochemistry, Medicine +14

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 1: Discovery and initial structure–activity relationships for 1-amino-2-phenyl-4-(piperidin-1-yl)butanes

Conrad P. Dorn, Paul E. Finke, Bryan Oates et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 89 citations · Full text

Initial Structure–activity Relationships, Biochemistry, Medicine +9

Biomimetic synthesis of enantiomerically pure D-myo-inositol derivatives

Steven L. Bender, Richard J. Budhu · Journal of the American Chemical Society · 1991 · 88 citations

Altmetric Attention Score, Organic Chemistry, Chemistry +16

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2: lead optimization affording selective, orally bioavailable compounds with potent Anti-HIV activity

Jeffrey J. Hale, Richard J. Budhu, Edward B. Holson et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 61 citations · Full text

Potent Anti-hiv Activity, Bioavailable Compounds, Pharmacology +9