Conrad P. Dorn

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution.

Manuel A. Navia, Brian M. McKeever, James P. Springer et al. · Proceedings of the National Academy of Sciences · 1989 · 237 citations

Life Sciences, Biochemistry, Molecular Biology +12

Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase

James B. Doherty, Bonnie M. Ashe, Lawrence W. Argenbright et al. · Nature · 1986 · 167 citations

Life Sciences, Immunology, Pharmacology +11

Direct fluorescent assay of urokinase and plasminogen activators of normal and malignant cells: kinetics and inhibitor profiles.

M.D. Zimmerman, J. P. Quigley, Bonnie M. Ashe et al. · Proceedings of the National Academy of Sciences · 1978 · 98 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs

Jeffrey J. Hale, Sander G. Mills, Malcolm MacCoss et al. · Journal of Medicinal Chemistry · 2000 · 95 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 1: Discovery and initial structure–activity relationships for 1-amino-2-phenyl-4-(piperidin-1-yl)butanes

Conrad P. Dorn, Paul E. Finke, Bryan Oates et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 89 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13