James B. Doherty

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Publications

Citations

1.2K

H-Index

Active since

1978

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

United States Military Academy

James B. Doherty is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacology, enzyme inhibition, and medicinal chemistry.

Publications per year

1978–2012

Publications

Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase

James B. Doherty, Bonnie M. Ashe, Lawrence W. Argenbright et al. · Nature · 1986 · 167 citations

Life Sciences, Immunology, Pharmacology +11

.beta.-Cyclodextrinylbisimidazole, a model for ribonuclease

Ronald Breslow, James B. Doherty, Geneviève Guillot et al. · Journal of the American Chemical Society · 1978 · 158 citations

Pharmacy, Chemistry, Molecular Biology +8

Crystallographie study of a β-lactam inhibitor complex with elastase at 1.84 Å resolution

Manuel A. Navia, James P. Springer, Tsau-Yen Lin et al. · Nature · 1987 · 102 citations

Life Sciences, Biochemistry, Medicinal Chemistry +14

Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase

John E. Stelmach, Luping Liu, Sangita B. Patel et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 81 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters

James B. Doherty, Bonnie M. Ashe, Peter L. Barker et al. · Journal of Medicinal Chemistry · 1990 · 73 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +10

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