Concepedia

Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy

Sabrina Angelini, Maria A. Pantaleo, Gloria Ravegnini, Corrado Zenesini, Giulia Cavrini, Margherita Nannini, Elena Fumagalli, Elena Palassini, Maristella Saponara, Monica Di Battista,

Pharmacological Research · 2012 · 76 citations · 24 references

DOI

Concepts

References

24

Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors

George D. Demetri, Margaret von Mehren, Charles D. Blanke et al. · New England Journal of Medicine · 2002 · 4.4K citations · Full text

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Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor

Michael C. Heinrich, Christopher L. Corless, George D. Demetri et al. · Journal of Clinical Oncology · 2003 · 2.3K citations

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Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation

Cristina R. Antonescu, Peter Besmer, Tianhua Guo et al. · Clinical Cancer Research · 2005 · 831 citations

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Molecular Correlates of Imatinib Resistance in Gastrointestinal Stromal Tumors

Michael C. Heinrich, Christopher L. Corless, Charles D. Blanke et al. · Journal of Clinical Oncology · 2006 · 814 citations

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Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor

Michael C. Heinrich, Robert G. Maki, Christopher L. Corless et al. · Journal of Clinical Oncology · 2008 · 806 citations · Full text

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