Peter Besmer

Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand

Beate Heissig, Koichi Hattori, Sérgio Dias et al. · Cell · 2002 · 1.7K citations · Full text

Progenitor Cells, Regenerative Medicine, Developmental Biology +11

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

Benoı̂t Chabot, Dennis A. Stephenson, Verne M. Chapman et al. · Nature · 1988 · 1.4K citations

Proto-oncogene C-kit, Knockout Mouse, Signal Transduction +11

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

Eric J. Huang, Karl Nocka, David R. Beier et al. · Cell · 1990 · 1.2K citations

Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation

Cristina R. Antonescu, Peter Besmer, Tianhua Guo et al. · Clinical Cancer Research · 2005 · 826 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

Fei-Hua Qiu, Partha Ray, Kate Brown et al. · The EMBO Journal · 1988 · 718 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +9