The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

Berkley A. Lynch, Nathalie Lambeng, Karl Nocka, +4

Proceedings of the National Academy of Sciences

New Antiepileptic DrugMolecular NeuroscienceAntiepileptic Drug LevetiracetamNeurophysiologyMedicine +13

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

Eric J. Huang, Karl Nocka, David R. Beier, +6

Cell

Gonadal expression of <i>c-kit</i> encoded at the W locus of the mouse

Katya Manova, Karl Nocka, Peter Besmer, +1

Development

The Dominant W ⁴² Spotting Phenotype Results from a Missense Mutation in the c- <i>kit</i> Receptor Kinase

Jimmy Tan, Karl Nocka, Prabir Ray, +2

Science

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

Paul V. Fish, P. Filippakopoulos, Gerwyn Bish, +16

Journal of Medicinal Chemistry

Histone ModificationsPharmaceutical ScienceDrug TargetBioorganic ChemistryFragment-derived Hit +18

Alternative splicing of interleukin-33 and type 2 inflammation in asthma

Erin Gordon, Laura J. Simpson, Cydney Rios, +14

Proceedings of the National Academy of Sciences

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyImmune Regulation +22

Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: Relationship to disease severity

Rekha Chaudhuri, Charles McSharry, Jeffrey D. Brady, +21

Journal of Allergy and Clinical Immunology

InflammationAsthmaAllergyAdvanced Lung DiseaseImmunology +2

Complement C3a, CpG Oligos, and DNA/C3a Complex Stimulate IFN-α Production in a Receptor for Advanced Glycation End Product-Dependent Manner

Benfang Helen Ruan, Xin Li, Aaron Winkler, +11

The Journal of Immunology

Suppression of immunoglobulin E–mediated allergic responses by regulator of G protein signaling 13

Geetanjali Bansal, Zhihui Xie, Sudhir Rao, +2

Nature Immunology

Signal TransductionAllergyImmune Cell DevelopmentImmune RegulationImmunology +11

Human Alveolar Macrophage Gene Responses to <i>Mycobacterium tuberculosis</i> Strains H37Ra and H37Rv

Richard F. Silver, Jessica Walrath, Hung Lee, +5

American Journal of Respiratory Cell and Molecular Biology