Concepedia

Transporter Gene Polymorphisms

Transporter Gene Polymorphisms is a genetic variation occurring in genes encoding membrane transport proteins that modulate the activity, expression, or function of drug transporters and thereby influence interindividual differences in drug disposition and response.

1.2K

Publications

78.1K

Citations

7.1K

Authors

1.8K

Institutions

Publications per year

2017–2026

120

Variants

Transporter Gene Polymorphism

Parents

Publications

1.2K

A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.5K citations · Full text

, , +15

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

, , +15

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

Yan Shu, Steven A. Sheardown, Chaline Brown et al. · Journal of Clinical Investigation · 2007 · 958 citations · Full text

, , +13

Functional variants of OCTN cation transporter genes are associated with Crohn disease

Vanya Peltekova, Richard F. Wintle, Laurence A. Rubin et al. · Nature Genetics · 2004 · 844 citations · Full text

, , +14

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects

Ingolf Cascorbi · Clinical Pharmacology & Therapeutics · 2001 · 749 citations

, , +15

1–5 of 1.2K

Authors

7.1K

  1. KM
    Kathleen M. Giacomini

    University of California, San Francisco, United States

    27 publications · 3.4K citations

    26

    h-index

  2. TE
    Thomas E. Ferrin

    University of California, San Francisco, United States

    18 publications · 1.9K citations

    18

    h-index

  3. SJ
    Susan J. Johns

    University of California, San Francisco, United States

    17 publications · 1.9K citations

    17

    h-index

  4. DS
    Doug Stryke

    University of California, San Francisco, United States

    14 publications · 1.5K citations

    14

    h-index

  5. DL
    Deanna L. Kroetz

    University of California, San Francisco, United States

    13 publications · 1.7K citations

    13

    h-index

1–5 of 7.1K

Institutions

1.8K

  1. University of California, San Francisco

    San Francisco, United States

    34 h-index

    243 publications

    19.7K citations

  2. University of Würzburg

    Würzburg, Germany

    20 h-index

    75 publications

    11.5K citations

  3. Harvard University

    Cambridge, United States

    19 h-index

    62 publications

    5K citations

  4. University of Bonn

    Bonn, Germany

    19 h-index

    78 publications

    5.5K citations

  5. Vanderbilt University

    Nashville, United States

    18 h-index

    93 publications

    10.5K citations

  6. Inserm

    Paris, France

    17 h-index

    101 publications

    8.8K citations

  7. University of Pennsylvania

    Philadelphia, United States

    17 h-index

    52 publications

    2.1K citations

  8. Heidelberg University

    Heidelberg, Germany

    17 h-index

    86 publications

    6.1K citations

1–8 of 1.8K

Venues

  1. Pharmacogenetics and Genomics

    46 publications · 4.3K citations

    35

    h-index

  2. PubMed

    Repository · 60 publications · 3.3K citations

    25

    h-index

  3. 23

    h-index

  4. Molecular Psychiatry

    23 publications · 3.6K citations

    20

    h-index

  5. PLoS ONE

    22 publications · 767 citations

    20

    h-index

1–5